Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) continue to wreak havoc across the globe.Higher transmissibility and immunologic resistance of VOCs bring unprecedented challenges to epidemic extinguishment.Here we describe a monoclonal antibody, 2G1, that neutralizes all current Scales VOCs and has s